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No ka mālama ʻili pono ʻana, ʻoiaʻiʻo, he mea pono ke loaʻa kahi manaʻo o nā mea hoʻohui, ʻaʻole wale ka hoʻolaha ʻana o ka huahana, akā, ʻo nā mea hoʻohui o ka huahana. I kēia lā, e kamaʻilio kākou e pili ana i ka "carnosine" o nā mea hoʻohui o nā huahana mālama ʻili.

He aha ka 'Carnosine'
He dipeptide ʻo Carnosine i haku ʻia me ka beta-alanine a me L-histidine, nona ka nui o ka ʻike i loko o nā ʻiʻo a me nā poloka lolo. Loaʻa iā Carnosine nā waiwai antioxidant kiʻekiʻe a hiki ke scavenge i nā radical manuahi i loko o ke kino.

Pehea e hana ai ka 'carnosine'
Hiki iā Carnosine ke hoʻonui i ke kūpaʻa o ka ʻili, mālama i ke kūlana ʻōpio o nā cell ma ka mālama ʻana i ka hana o nā cell i ka hui spectrum piha a me nā kūlana radical manuahi, paipai i ka hana ʻana o ka collagen, a mālama i ka elastic o ka ʻili.

Ke kuleana o 'carnosine'
Hiki iā Carnosine ke hoʻonui i ke kūpaʻa o ka ʻili, mālama i ke kūlana ʻōpiopio o nā cell ma ka mālama ʻana i ka hana o nā cell i loko o ka hui spectrum piha a me nā kūlana radical manuahi, paipai i ka hana ʻana o ka collagen, a mālama i ka elastic o ka ʻili. ʻO ke ʻano kemika oL-carnosineʻo ia ka hoʻokumu ʻia ʻana o ka beta-alanine a me L-histidine ma o ka hana a carnosine synthase. Loaʻa iā Carnosine nā manaʻolana noi ākea ma nā kahua o ka lāʻau lapaʻau, ka mālama ola kino, a me ka hoʻomaʻemaʻe ma muli o kona mau waiwai antioxidant, nā hopena scavenging radical manuahi, chelation me nā metala hoʻololi, neuroprotection, hoʻolaha ho'ōla ʻeha, a me ka anti-aging.

1. Ka hoʻohana ʻana o ka carnosine i ka ʻoihana meaʻai
ʻO ka ʻāpana nui o ka ʻaila i ka meaʻai he hui ʻana o nā ʻano glycerides waikawa momona like ʻole. Ma muli o ka hopena radical manuahi o nā glycerides waikawa momona unsaturated i ka wā e mālama ai, ua hana ʻia nā peroxides a me nā aldehydes ʻala a i ʻole nā ​​​​waikawa carboxylic me nā kaulahao kalapona pōkole. No laila, ʻo ka ʻai ʻana i nā meaʻai i loaʻa nā peroxides momona e hoʻolaha hou aku i ka lipid peroxidation i loko o ke kino o ke kanaka a hoʻoulu i nā maʻi like ʻole. No laila, hoʻohana pinepine ʻia ka butylated hydroxyanisole, dibutylated hydroxytoluene, propyl gallate, a me nā mea ʻē aʻe i ka hana ʻana a me ka mālama ʻana i ka meaʻai e pale aku i ka peroxidation momona, akā e hoʻemi ʻia ko lākou pono i ke kaʻina hana hoʻomehana o ka hana ʻana i ka meaʻai, a he ʻawaʻawa iki kona. ʻAʻole hiki i ka L-carnosine ke pale wale i ka oxidation momona, akā he mau hana palekana a mālama ola kino kiʻekiʻe hoʻi. No laila, he waiwai nui a he antioxidant meaʻai kūpono ʻo L-carnosine.
2. Ka hoʻohana ʻana o ka carnosine i ka lāʻau lapaʻau a me ka mālama ola kino
(1) Carnosine a me ka Antioxidant

ʻAʻole hiki iā Carnosine ke hoʻohana wale i ke apo imidazole N atom a me ka peptide bond N atom ma nā koena histidine e chelate i nā ion metala a kāohi i ka oxidation momona i hoʻokumu ʻia e nā ion metala, akā ʻo ka histidine ma ke kaulahao ʻaoʻao o carnosine he hiki ke hopu i nā radical hydroxyl. Hiki iā ia ke kāohi i ka oxidation o ka momona i hoʻokumu ʻia e nā ion non-metal. No laila, ma ke ʻano he mea hana antioxidant multifunctional, hiki iā carnosine ke pale paʻa i ka membrane cell a he mea hoʻoheheʻe radical manuahi wai-soluble. , hiki ke pale i ka peroxidation o ka membrane cell. Ke hoʻohālikelike ʻia me nā antioxidants biological ʻē aʻe e like me VC, ʻoi aku ka ikaika o ka antioxidant o carnosine. Ma waho aʻe o ka pale ʻana i ke kaʻina hana peroxidation o ka membrane cell, hiki iā carnosine ke kāohi i kahi moʻo o nā hopena peroxidation intracellular ʻē aʻe, ʻo ia hoʻi, hiki iā carnosine ke kāohi i kēlā me kēia ʻanuʻu o ka hopena oxidation ma ke kaulahao peroxidation holoʻokoʻa i loko o ke kino. ʻO ke kuleana o nā antioxidants e like me VC ka pale ʻana i nā radical manuahi mai ke komo ʻana i loko o ke kino, ʻo ia hoʻi, hiki iā lākou ke pale wale i ke kaʻina hana peroxidation wai o ka membrane cell, a ʻaʻohe mea hiki ke hana no nā radical manuahi i komo i loko o ke kelepona.
(2) Carnosine a me ka ʻōpū ʻōpū

ʻO ka maʻi ʻōpū peptic kahi maʻi maʻi mau loa o ka ʻōnaehana hoʻoheheʻe honua, a ʻaʻole maopopo loa nā kumu kikoʻī e hoʻoulu ai i nā ʻōpū i kēia manawa, akā manaʻoʻiʻo ka pathology he mau mea hoʻouka kaua (e like me ka waikawa gastric, ka huna ʻana o ka pepsin, ka maʻi Helicobacter pylori) a me ka pale ʻana a i ʻole ke kelepona i hana ʻia e ka nele o nā mea pale (ka huna ʻana o ka mucus, ka huna ʻana o ka bicarbonate, ka hana ʻana o ka prostaglandin). ʻO ke ʻano pale kūlohelohe o ka ʻōpū: hana ia i kahi papa mānoanoa o ka mucosa gastric e hana ana ma ke ʻano he pale pale e pale i nā cell i loko o ka lining. Mālama ka huna mau ʻana o ka membrane mucous i ka ʻōpū, akā hiki i ka huna nui ke hana i nā ʻōpū gastric. Ua ʻike ʻia nā haʻawina hiki i ka zinc-carnosine i lawe ʻia me ka meaʻai ke pale pono i nā ʻōpū, hiki iā ia ke mālama pono i ka pono o ka ʻōpū a me kāna ʻano pale kūlohelohe, ʻo kēia ma muli o nā waiwai antioxidant o carnosine, ka hoʻopaʻa ʻana o ka membrane, ka hoʻoponopono ʻana i nā waiwai Pharmacological o ka pale ʻana a me ka hoʻoponopono ʻana i nā ʻiʻo. Wahi a nā hoʻokolohua lapaʻau, ma hope o ka lawe ʻana i ka zinc-carnosine no ʻewalu pule, 70% o nā maʻi i lawe i ka lāʻau lapaʻau i hōʻike i ka hoʻomaikaʻi nui ʻana, a ua hoʻomaikaʻi ʻia ka 65% o nā ʻōpū gastric ma o ka gastroscopy.
(3) Carnosine a me ka hoʻoponopono ʻana i ka pale ʻana

ʻO ka pane ʻana o ka pale kino he hana physiological e mālama ana i ka homeostasis a hoʻoponopono ʻia e nā mea hana physiologically i loko o nā meaola ola. Pili nā Immunomodulators i ka mālama ʻana i kahi papa o nā maʻi i hoʻokumu ʻia e ka hana ʻole o ka pale kino, a hoʻohana ʻia e hoʻihoʻi i ka pane ʻana o ka pale kino, kāohi i kona emi ʻana maʻamau a kāohi paha i kāna pane wikiwiki. ʻO ka hapa nui o nā immunomodulators e kū nei ua synthesized ʻia e nā ʻano hana synthesis kemika, nona kekahi mau hopena ʻawahia a me nā hopena ʻaoʻao. Ua hōʻike ʻia nā haʻawina he hana immunomodulatory ko carnosine, a ʻo ia wale nō ka mea hana physiologically i loaʻa a hiki i kēia manawa no ka immunomodulation, a ua hoʻohana nui ʻia i ka mālama ʻana i nā maʻi like ʻole a me nā maʻi i hoʻokumu ʻia e ka pale kino maʻamau.