SHIKONIN CAS 517-89-5 Shikonine

CAS:517-89-5

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5,8-Dihydroxy-2-[(R)-1-hydroxy-4-methyl-3-pentenyl]-1,4-naphthalenedione;TokyoViolet;(R)-5,8-Dihydroxy-2-(1-hydroxy-4-Methylpent-3-en-1-yl)naphthalene-1,4Chemicalbook-dione;SHIKONIN(AS);Shikonin,froMArnebiasp.;(-)-ShikoninChina;Shikonine;Shikonin5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione

Inoa Lama: Unilong
Kahi o ke kumu: Shandong, Kina
Maʻemaʻe: 99%

Inoa huahana: SHIKONIN

Hoʻopili ʻana: 25kgs/pahu

Hoʻouna: I kēia manawa koke

MF:C16H16O5

MW:288.3

Waiho i kāu leka

Nā kikoʻī huahana

Hoʻoiho

Nā Lepili Huahana

He aha ka meaSHIKONIN

ʻO ke aniani nila poni-ʻeleʻele, kiko heheʻe 147 ℃, ka wili ʻana o ka ʻike αD20=+135°(benzene). Hiki ke hoʻoheheʻe ʻia i loko o ka phenethyl ether, acetone, chloroform, methanol, ethanol, glycerol, nā aila holoholona a me nā mea kanu a me nā hopena wai alkaline, ʻaʻole hiki ke hoʻoheheʻe ʻia i ka wai. Hoʻololi ke kala me ka waiwai Ph, me ka waiwai Ph o 4-6 he ʻulaʻula, ka waiwai Ph o 8 he poni, a me ka waiwai Ph o 10-12 he polū. Kūpaʻa maikaʻi i ke kukui, kūpaʻa wela a me ke kūpaʻa oxidation, paʻa ʻole i ka hoʻemi ʻana i ka nui, a me ka poni ʻeleʻele i ka hihia o nā ion hao. Loaʻa iā ia kahi hopena antibacterial.

Nā kikoʻī oSHIKONIN

CAS	517-89-5
Nā Inoa ʻē aʻe	ʻO Shikonine
helehelena	pauka poni
Maʻemaʻe	99%
Waihoʻoluʻu	poni
Ka Waihona	Ka Waihona Maloʻo Anu
Pūʻolo	25kg/ʻeke
Noi	Meaʻai

Hoʻohana ʻia oSHIKONIN

(1) Ka hopena hypoglycemic Loaʻa i ka lau lau o ka comfrey a me ka polysaccharide (A, B, C) o ka comfrey ka hopena hypoglycemic maopopo.

(2) Ka hopena bacteriostatic Loaʻa i ka Lithospermum kahi hopena pale i ka maʻi Jingke 68-1 in vitro, a he hopena pale i ka Staphylococcus aureus. Ua aʻo ʻia ka hopena anti-parainfluenza virus o levoshikonin ma o ka hemagglutination reaction a me ke ʻano cytopathic. Ua hōʻike nā hopena he haʻahaʻa kona ʻawahia i loko o ka pae hoʻohuihui i hoʻohana ʻia i ka hoʻokolohua, a he hana anti-influenza virus in vitro a me ka pepehi pololei ʻana i ka maʻi parainfluenza.

(3) Nā hopena i ke kāpili ʻana o ke koko: ʻO ka hoʻokomo ʻana i nā ʻāpana shikonin (shikonin, acetylshikonin) i loko o ka ʻōpū, ʻaʻole ia e hoʻopilikia i ka manawa kāpili ʻana o ke koko, akā hiki ke pale i ka hopena anticoagulant o ka heparin.

(4) Ka hopena anti-tumor Loaʻa i ka Comfrey extract kahi hopena inhibitory i ke kahua hope (G2 phase) o ka synthesis DNA i loko o nā cell Hela.

(5) Ka hopena antitumor Hoʻopale ʻo Shikonin i ka ulu ʻana, hoʻolaha i ka apoptosis a hoʻoulu i ka hoʻopau ʻana o ke kaʻina hana cell i loko o nā laina cell choriocarcinoma kanaka i hoʻoulu ʻia i ka lāʻau lapaʻau (JAR/MTX) in vitro. Hōʻike nā hoʻokolohua e piʻi ana ka nui o shikonin me ka nui. A me ka hoʻolōʻihi ʻana o ka manawa hana, ua piʻi nui ka nui o ka pale ʻana o ka ulu ʻana o nā cell choriocarcinoma i kūʻē i ka lāʻau lapaʻau.

(6) Nā hopena ma ka hoʻokahe ʻana o ka hormone Ua hōʻike ka hopena o shikonin ma ka hana o ke axis hypothalamic-pituitary-gonadal i nā ʻiole wahine ʻōpio ua haʻahaʻa loa nā pae hormone serum i ka hui shikonin ma mua o nā mea i loko o ka hui kaohi maikaʻi ʻole, a ʻaʻohe ʻokoʻa koʻikoʻi i hoʻohālikelike ʻia me ka hui kaohi maikaʻi. Hōʻike ia hiki i ka shikonin ke kāohi i ka hana o ke axis hypothalamic-pituitary-gonadal i nā ʻiole.

(7) Ka hopena antioxidant Ua ana kekahi poʻe noiʻi i ka hiki ke scavenging o shikonin i ka superoxide radical (O2-) a me 1,1-diphenyl-2-picrophenhydrazine radical (DPPH), a me kona hopena ma ka β-- Inhibition o ka ʻōnaehana autooxidation carotene/linoleic acid. Ua hōʻike nā hopena he ikaika ka hiki ke scavenging o shikonin i ka DPPH a me O2-, a he hopena inhibitory maopopo i ka ʻōnaehana auto-oxidation o ka β-carotene/linoleic acid. Ka mana antioxidant ikaika.