Metronidazole CAS 443-48-1
ʻO ka Metronidazole he keʻokeʻo a i ʻole melemele liʻiliʻi a i ʻole ka pauka crystalline; He ʻala iki, he ʻawaʻawa a paʻakai iki. Hiki ke hoʻoheheʻe ʻia i loko o ka ethanol, hiki ke hoʻoheheʻe iki ʻia i ka wai a i ʻole chloroform, a hiki ke hoʻoheheʻe iki ʻia i ka etera. ʻO Metronidazole kahi hui heterocyclic me ka alkalinity a me ka haʻahaʻa haʻahaʻa o ka wai. Wahi a ka loina prodrug, hana ʻia ka metronidazole i loko o ka potassium phosphate ester, kahi e hoʻonui ai i ka hoʻoheheʻe wai a hiki ke hoʻohana ʻia ma ke ʻano he hopena injection.
| 'ikamu | Hōʻike |
| Lae paila | 301.12°C (manaʻo koʻikoʻi) |
| ʻO ka mānoanoa | 1.3994 (manaʻo koʻikoʻi) |
| Lae hehee | 159-161 °C (kukui) |
| pKa | pKa 2.62(H2O,t =25±0.2, |
| Nā kūlana mālama | 2-8°C |
He hopena antibacterial ikaika ka Metronidazole i ka hapa nui o nā maʻi bacteria anaerobic a hoʻohana ʻia e mālama i ka amoebiasis, trichomoniasis, a me nā maʻi bacteria anaerobic. Hoʻohana ʻia no ka mālama ʻana i ka trichomoniasis vaginal a ua hoʻohana ʻia no ka amoebiasis ʻōpū a me extraintestinal mai ka makahiki 1970. He kiʻekiʻe kona hopena, haʻahaʻa ka ʻona, a hoʻohana nui ʻia. Loaʻa nā hopena mutagenic a me teratogenic i nā hoʻokolohua holoholona.
Hoʻopili pinepine ʻia i ka 25kg / pahu, a hiki ke hana ʻia i ka pōʻai maʻamau.
Metronidazole CAS 443-48-1
Metronidazole CAS 443-48-1
