ʻO ka hale hana Kina no ka mea hana lāʻau lapaʻau waena, lāʻau lapaʻau waena, kiʻekiʻe kiʻekiʻe Prilocaine pauda mea hoʻolako.
ʻO kā mākou mau uku e hōʻemi i ke kūʻai aku ʻana i nā kumukūʻai, ka hui loaʻa kālā, QC kūikawā, nā hale paʻa paʻa, nā lawelawe ʻoi aku ka maikaʻi no China Factory for Pharmaceutical Intermediate Manufacturer, Pharmaceutical Intermediate, High Grade Prilocaine Powder Supplier, hiki iā mākou ke hoʻoponopono i nā pilikia o kā mākou mea kūʻai aku a hana i ka waiwai no kā mākou mea kūʻai. Inā makemake ʻoe i ka ʻoihana maikaʻi a me ke ʻano kiʻekiʻe, pls koho iā mākou, mahalo!
ʻO kā mākou uku e hōʻemi i nā kumukūʻai kūʻai aku, ka hui loaʻa kālā, QC kūikawā, nā hale hana paʻa, nā lawelawe ʻoi aku ka maikaʻi noLtd., ʻO Wuhan Jingkang Technology Co., Manaʻo kā mākou hui i "nā kumukūʻai kūpono, ka manawa hana kūpono a me ka lawelawe ma hope o ke kūʻai aku" e like me kā mākou kumu. Manaʻolana mākou e hui pū me nā mea kūʻai aku no ka hoʻomohala ʻana a me nā pōmaikaʻi. Aloha mākou i nā mea kūʻai aku e hoʻopili iā mākou.
2,5-Dimethoxybenzaldehydehe pauda crystalline melemele māmā me ke kaumaha molekala o 166.18 a me kahi paila o 146°C. Hiki ke hoʻoheheʻe ʻia i loko o nā mea hoʻoheheʻe organik e like me ka ethanol a me ka ether. Hoʻohana nui ʻia ia ma ke ʻano he pharmaceutical intermediate.
| MEA | KANAWAI |
| Ka nana aku | Paʻa hina a melemele |
| NMR | Hoʻokō |
| Maemae | >98% |
| Lae hehee | 46-48 °C (māmā) |
| ʻAno wai | <0.5% |
Ma waho aʻe o ka oxidized a hoʻemi ʻia i ka 2,5-dimethoxybenzoic acid, benzonitrile a i ʻole benzyl alcohol,2,5-dimethoxybenzaldehydeloaʻa iā ia iho ka waiwai noi kūʻokoʻa. Ma ka hana ʻana me nā mea me nā ʻano hui hana like ʻole, hiki ke loaʻa nā molekala lāʻau me nā ʻano like ʻole a me nā hopena like ʻole. ʻO ka maʻi o Parkinson (PD) he maʻi neurodegenerative maʻamau, a ʻo kāna mau hōʻailona koʻikoʻi e pili ana i ka haʻalulu ʻiʻo, ʻoʻoleʻa, paʻakikī o ka neʻe ʻana, ke kū ʻana o ke kino a me nā pilikia kaulike. ʻO ka hoʻomohala hou aʻe e alakaʻi i ka ʻike, ka ʻike, nā pilikia hoʻomanaʻo a me ka dementia maopopo. I kēia manawa, ʻo ka mālama ʻana i ka PD ka mea nui e pili ana i ka lāʻau lapaʻau, ka lāʻau lapaʻau a me ka lāʻau gene. I ka lāʻau lapaʻau, ua ʻike ʻia ka hopena maikaʻi o ka phenamidine i ka PD, me ka haʻahaʻa haʻahaʻa a me ka palekana maikaʻi, a ʻo ka synthesis o ka phenamidine e pono ai ka hoʻohana2,5-dimethoxybenzaldehydei mea hoʻomaka.
E like me ke ʻano synthesis i hōʻike ʻia ma ka palapala,2,5-dimethoxybenzaldehydeloaʻa nui ʻia ma ka hana ʻana i ka 1,4-dimethoxybenzene me kahi mea hana formylation. ʻO nā mea hana formylation ka (1) kahi hui o 1,1-dichloromethyl ether a me titanium tetrachloride; (2) kahi hui o N,N-dimethylformamide a me phosphorus oxychloride, kahi hui o N,N-dimethylformamide a me oxalyl chloride; (3) kahi hui o N,N-dimethylformamide a me thionyl chloride a i ʻole ka hui ʻana o ka urotropine a me ka magnesium chloride. Eia nō naʻe, pono kēia mau ʻano i ka hoʻohana ʻana i ka nui o ka titanium tetrachloride, phosphorus oxychloride a i ʻole thionyl chloride. ʻAʻole paʻa a maʻalahi kēia mau reagents, a ua hoʻokuʻu ʻia ka nui o ke kinoea hydrochloric acid i ka wā o ka hopena, ʻaʻole ia e pili i ke kaiapuni a loaʻa nā koi kiʻekiʻe no ke kaʻina hana.
Ua manaʻo ʻia kahi ala synthesis hou. Hoʻohana kēia ʻano hana i ka 1,4-dimethoxybenzene a me ka formaldehyde e like me nā mea maka, a hana i kahi hopena hoʻohui photooxidative i ke alo o ka oxygen a me ka catalyst ma lalo o ka irradiation kukui polū e hoʻohui pono i ka 2,5-dimethoxybenzaldehyde. Hoʻohana kēia ʻano i ka oxygen a i ʻole ka ea ma ke ʻano he oxidant, ʻaʻole e hoʻopuka i ke kinoea ʻakika, a pili i ke kaiapuni. Eia kekahi, hoʻohana kēia ʻano i ka cobalt cheap ma ke ʻano he catalyst, he haʻahaʻa i ke kumukūʻai a kūpono no ka noi ʻoihana.
25kgs / pahu, 9tons / 20' pahu
25kgs / eke, 20tons / 20'container
ʻO kā mākou mau uku e hōʻemi i ke kūʻai aku ʻana i nā kumukūʻai, ka hui loaʻa kālā, QC kūikawā, nā hale paʻa paʻa, nā lawelawe ʻoi aku ka maikaʻi no China Factory for Pharmaceutical Intermediate Manufacturer, Pharmaceutical Intermediate, High Grade Prilocaine Powder Supplier, hiki iā mākou ke hoʻoponopono i nā pilikia o kā mākou mea kūʻai aku a hana i ka waiwai no kā mākou mea kūʻai. Inā makemake ʻoe i ka ʻoihana maikaʻi a me ke ʻano kiʻekiʻe, pls koho iā mākou, mahalo!
Hale Hana Kina noʻO Wuhan Jingkang Technology Co., Ltd, Ke manaʻo nei kā mākou hui i "nā kumukūʻai kūpono, ka manawa hana kūpono a me ka lawelawe ma hope o ke kūʻai aku" e like me kā mākou kumu. Manaʻolana mākou e hui pū me nā mea kūʻai aku no ka hoʻomohala ʻana a me nā pōmaikaʻi. Aloha mākou i nā mea kūʻai aku e hoʻopili iā mākou.
