2019 kumu kūʻai nui 2, 5-Dimethoxybenzaldehyde Pauda CAS 93-02-7
Me kā mākou ʻenehana alakaʻi e like me kā mākou ʻuhane o ka hana hou, ka hui like ʻana, nā pōmaikaʻi a me ka hoʻomohala ʻana, e kūkulu mākou i kahi wā e hiki mai ana me kāu ʻoihana hanohano no ke kumukūʻai kūʻai 2019.2, 5-Dimethoxybenzaldehyde Pauda CAS 93-02-7, ʻO ke kumu o kā mākou hui e hāʻawi mau i nā mea kūʻai kiʻekiʻe, lawelawe loea, a me ka kamaʻilio pololei. Welina mai e nā hoaaloha a pau e hoʻokolokolo no ka hana ʻana i kahi hui ʻoihana lōʻihi.
Me kā mākou ʻenehana alakaʻi e like me ko mākou ʻuhane o ka hana hou, hui like ʻana, nā pōmaikaʻi a me ka hoʻomohala ʻana, e kūkulu mākou i kahi wā e hiki mai ana me kāu ʻoihana mahalo ʻia no , I kēia manawa ua loaʻa iā mākou kahi inoa maikaʻi no nā mea paʻa maikaʻi, hoʻokipa maikaʻi ʻia e nā mea kūʻai aku ma ka home a ma waho. E alakaʻi ʻia kā mākou hui e ka manaʻo o "Standing in Domestic Markets, Walking into International Markets". Manaʻolana mākou e hiki iā mākou ke hana ʻoihana me nā mea hana kaʻa, nā mea kūʻai ʻāpana kaʻa a me ka hapa nui o nā hoa hana ma ka home a ma waho. Manaʻo mākou i ka launa pū ʻana a me ka hoʻomohala maʻamau!
ʻO 2,5-Dimethoxybenzaldehyde kahi pauka crystalline melemele māmā me ke kaumaha molekala o 166.18 a me kahi paila o 146°C. Hiki ke hoʻoheheʻe ʻia i loko o nā mea hoʻoheheʻe organik e like me ka ethanol a me ka ether. Hoʻohana nui ʻia ia ma ke ʻano he pharmaceutical intermediate.
| MEA | KANAWAI |
| Ka nana aku | Paʻa hina a melemele |
| NMR | Hoʻokō |
| Maemae | >98% |
| Lae hehee | 46-48 °C (māmā) |
| ʻAno wai | <0.5% |
Ma waho aʻe o ka oxidized a i hoʻemi ʻia i2,5-dimethoxybenzoic acid, benzonitrile a i ʻole benzyl waiʻona, 2,5-dimethoxybenzaldehyde ponoʻī nō hoʻi ka waiwai hoʻohana kūikawā. Ma ka hana ʻana me nā mea me nā ʻano hui hana like ʻole, hiki ke loaʻa nā molekala lāʻau me nā ʻano like ʻole a me nā hopena like ʻole. ʻO ka maʻi o Parkinson (PD) he maʻi neurodegenerative maʻamau, a ʻo kāna mau hōʻailona koʻikoʻi e pili ana i ka haʻalulu ʻiʻo, ʻoʻoleʻa, paʻakikī o ka neʻe ʻana, ke kū ʻana o ke kino a me nā pilikia kaulike. ʻO ka hoʻomohala hou aʻe e alakaʻi i ka ʻike, ka ʻike, nā pilikia hoʻomanaʻo a me ka dementia maopopo. I kēia manawa, ʻo ka mālama ʻana i ka PD ka mea nui e pili ana i ka lāʻau lapaʻau, ka lāʻau lapaʻau a me ka lāʻau gene. I ka lāʻau lapaʻau, ua loaʻa ka phenamidine i ka hopena maikaʻi ma PD, me ka haʻahaʻa haʻahaʻa a me ka palekana maikaʻi, a ʻo ka synthesis o phenamidine e pono ai ka hoʻohana ʻana i ka 2,5-dimethoxybenzaldehyde i mea hoʻomaka.
Wahi a ke ʻano hana synthesis i hōʻike ʻia ma ka palapala, loaʻa ka 2,5-dimethoxybenzaldehyde ma ka hana ʻana i ka 1,4-dimethoxybenzene me kahi mea hana formylation. ʻO nā mea hana formylation ka (1) kahi hui o 1,1-dichloromethyl ether a me titanium tetrachloride; (2) kahi hui o N,N-dimethylformamide a me phosphorus oxychloride, kahi hui o N,N-dimethylformamide a me oxalyl chloride; (3) kahi hui o N,N-dimethylformamide a me thionyl chloride a i ʻole ka hui ʻana o ka urotropine a me ka magnesium chloride. Eia nō naʻe, pono kēia mau ʻano i ka hoʻohana ʻana i ka nui o ka titanium tetrachloride, phosphorus oxychloride a i ʻole thionyl chloride. ʻAʻole paʻa a maʻalahi kēia mau reagents, a ua hoʻokuʻu ʻia ka nui o ke kinoea hydrochloric acid i ka wā o ka hopena, ʻaʻole ia e pili i ke kaiapuni a loaʻa nā koi kiʻekiʻe no ke kaʻina hana.
Ua manaʻo ʻia kahi ala synthesis hou. Hoʻohana kēia ʻano hana i ka 1,4-dimethoxybenzene a me ka formaldehyde e like me nā mea maka, a hana i kahi hopena hoʻohui photooxidative i ke alo o ka oxygen a me ka catalyst ma lalo o ka irradiation kukui polū e hoʻohui pono i ka 2,5-dimethoxybenzaldehyde. Hoʻohana kēia ʻano i ka oxygen a i ʻole ka ea ma ke ʻano he oxidant, ʻaʻole e hoʻopuka i ke kinoea ʻakika, a pili i ke kaiapuni. Eia kekahi, hoʻohana kēia ʻano i ka cobalt cheap ma ke ʻano he catalyst, he haʻahaʻa i ke kumukūʻai a kūpono no ka noi ʻoihana.
25kgs / pahu, 9tons / 20' pahu
25kgs / eke, 20tons / 20'container
Me kā mākou ʻenehana alakaʻi e like me kā mākou ʻuhane o ka hana hou, ka hui like ʻana, nā pōmaikaʻi a me ka hoʻomohala ʻana, e kūkulu mākou i kahi wā e hiki mai ana me kāu ʻoihana hanohano no ke kumukūʻai kūʻai 2019.2, 5-Dimethoxybenzaldehyde Pauda CAS 93-02-7, ʻO ke kumu o kā mākou hui e hāʻawi mau i nā mea kūʻai kiʻekiʻe, lawelawe loea, a me ka kamaʻilio pololei. Welina mai e nā hoaaloha a pau e hoʻokolokolo no ka hana ʻana i kahi hui ʻoihana lōʻihi.
2019 kuai nui 2 5-Dimethoxybenzaldehyde a me2 5-Dimethoxybenzaldehyde Pauda,I kēia manawa, loaʻa iā mākou kahi inoa maikaʻi no nā mea paʻa maikaʻi, hoʻokipa maikaʻi ʻia e nā mea kūʻai aku ma ka home a ma waho. E alakaʻi ʻia kā mākou hui e ka manaʻo o "Standing in Domestic Markets, Walking into International Markets". Manaʻolana mākou e hiki iā mākou ke hana ʻoihana me nā mea hana kaʻa, nā mea kūʻai ʻāpana kaʻa a me ka hapa nui o nā hoa hana ma ka home a ma waho. Manaʻo mākou i ka launa pū ʻana a me ka hoʻomohala maʻamau!
