2019 Kiekie Kiekie Kiekie Kiekie 93-02-7 2, 5-Dimethoxybenzaldehyde CAS 93 02 7
ʻO kā mākou mau ʻimi mau ʻo ke ʻano o ka "manaʻo i ka mākeke, e nānā i ka maʻamau, e pili ana i ka ʻepekema" a me ka manaʻo o ka "maikaʻi ke kumu, manaʻoʻiʻo i ka mua a me ka hoʻokele ʻana i ka holomua" no 2019 High Quality High Quality 93-02-72, 5-Dimethoxybenzaldehyde CAS 93 02 7, No laila, hiki iā mākou ke hālāwai i nā nīnau likeʻole mai nā mea kūʻai likeʻole. Pono ʻoe e ʻimi i kā mākou ʻaoʻao pūnaewele e nānā i ka ʻike hou aku mai kā mākou huahana.
ʻO kā mākou mau ʻimi mau ʻo ke ʻano o ka "noʻonoʻo i ka mākeke, e nānā i ka maʻamau, e nānā i ka ʻepekema" a me ke kumumanaʻo o "ka maikaʻi o ke kumu, manaʻoʻiʻo i ka mua a me ka hoʻokele ʻana i ka holomua"CAS 93 02 7 a me 2 5-Dimethoxybenzaldehyde, Nui nā ʻano mea kūʻai like ʻole i loaʻa iā ʻoe ke koho ponoʻī, hiki iā ʻoe ke hana kūʻai hoʻokahi ma ʻaneʻi. A ʻae ʻia nā kauoha i hoʻonohonoho ʻia. ʻO ka ʻoihana maoli ka loaʻa ʻana o ke kūlana win-win, inā hiki, makemake mākou e hāʻawi i ke kākoʻo hou aku no nā mea kūʻai aku. Welina mai nā mea kūʻai maikaʻi a pau e kamaʻilio i nā kikoʻī o nā mea kūʻai me mākou!!
ʻO 2,5-Dimethoxybenzaldehyde kahi pauka crystalline melemele māmā me ke kaumaha molekala o 166.18 a me kahi paila o 146°C. Hiki ke hoʻoheheʻe ʻia i loko o nā mea hoʻoheheʻe organik e like me ka ethanol a me ka ether. Hoʻohana nui ʻia ia ma ke ʻano he pharmaceutical intermediate.
| MEA | KANAWAI |
| Ka nana aku | Paʻa hina a melemele |
| NMR | Hoʻokō |
| Maemae | >98% |
| Lae hehee | 46-48 °C (māmā) |
| ʻAno wai | <0.5% |
Ma kahi o ka oxidized a i hoʻemi ʻia i ka 2,5-dimethoxybenzoic acid, benzonitrile a i ʻole benzyl alcohol,2,5-dimethoxybenzaldehydeloaʻa iā ia iho ka waiwai noi kūikawā. Ma ka hana ʻana me nā mea me nā ʻano hui hana like ʻole, hiki ke loaʻa nā molekala lāʻau me nā ʻano like ʻole a me nā hopena like ʻole. ʻO ka maʻi o Parkinson (PD) he maʻi neurodegenerative maʻamau, a ʻo kāna mau hōʻailona koʻikoʻi e pili ana i ka haʻalulu ʻiʻo, ʻoʻoleʻa, paʻakikī o ka neʻe ʻana, ke kū ʻana o ke kino a me nā pilikia kaulike. ʻO ka hoʻomohala hou aʻe e alakaʻi i ka ʻike, ka ʻike, nā pilikia hoʻomanaʻo a me ka dementia maopopo. I kēia manawa, ʻo ka mālama ʻana i ka PD ka mea nui e pili ana i ka lāʻau lapaʻau, ka lāʻau lapaʻau a me ka lāʻau gene. I ka lāʻau lapaʻau, ua loaʻa ka phenamidine i ka hopena maikaʻi ma PD, me ka haʻahaʻa haʻahaʻa a me ka palekana maikaʻi, a ʻo ka synthesis o phenamidine e pono ai ka hoʻohana ʻana i ka 2,5-dimethoxybenzaldehyde i mea hoʻomaka.
E like me ke ʻano synthesis i hōʻike ʻia ma ka palapala,2,5-dimethoxybenzaldehydeloaʻa ma ka hana ʻana i ka 1,4-dimethoxybenzene me kahi mea hana formylation. ʻO nā mea hana formylation ka (1) kahi hui o 1,1-dichloromethyl ether a me titanium tetrachloride; (2) kahi hui o N,N-dimethylformamide a me phosphorus oxychloride, kahi hui o N,N-dimethylformamide a me oxalyl chloride; (3) kahi hui o N,N-dimethylformamide a me thionyl chloride a i ʻole ka hui ʻana o ka urotropine a me ka magnesium chloride. Eia nō naʻe, pono kēia mau ʻano i ka hoʻohana ʻana i ka nui o ka titanium tetrachloride, phosphorus oxychloride a i ʻole thionyl chloride. ʻAʻole paʻa a maʻalahi kēia mau reagents, a ua hoʻokuʻu ʻia ka nui o ke kinoea hydrochloric acid i ka wā o ka hopena, ʻaʻole ia e pili i ke kaiapuni a loaʻa nā koi kiʻekiʻe no ke kaʻina hana.
Ua manaʻo ʻia kahi ala synthesis hou. Hoʻohana kēia ʻano hana i ka 1,4-dimethoxybenzene a me ka formaldehyde e like me nā mea maka, a hana i kahi hopena hoʻohui photooxidative i ke alo o ka oxygen a me ka catalyst ma lalo o ka irradiation kukui polū e hoʻohui pono i ka 2,5-dimethoxybenzaldehyde. Hoʻohana kēia ʻano i ka oxygen a i ʻole ka ea ma ke ʻano he oxidant, ʻaʻole e hoʻopuka i ke kinoea ʻakika, a pili i ke kaiapuni. Eia kekahi, hoʻohana kēia ʻano i ka cobalt cheap ma ke ʻano he catalyst, he haʻahaʻa i ke kumukūʻai a kūpono no ka noi ʻoihana.
25kgs / pahu, 9tons / 20' pahu
25kgs / eke, 20tons / 20'container
ʻO kā mākou mau ʻimi mau ʻo ke ʻano o ka "manaʻo i ka mākeke, e nānā i ka maʻamau, e pili ana i ka ʻepekema" a me ka manaʻo o ka "maikaʻi ke kumu, manaʻoʻiʻo i ka mua a me ka hoʻokele ʻana i ka holomua" no 2019 High Quality High Quality 93-02-72, 5-Dimethoxybenzaldehyde CAS 93 02 7, No laila, hiki iā mākou ke hālāwai i nā nīnau likeʻole mai nā mea kūʻai likeʻole. Pono ʻoe e ʻimi i kā mākou ʻaoʻao pūnaewele e nānā i ka ʻike hou aku mai kā mākou huahana.
2019 kūlana kiʻekiʻeCAS 93 02 7 a me 2 5-Dimethoxybenzaldehyde, Nui nā ʻano mea kūʻai like ʻole i loaʻa iā ʻoe ke koho ponoʻī, hiki iā ʻoe ke hana kūʻai hoʻokahi ma ʻaneʻi. A ʻae ʻia nā kauoha i hoʻonohonoho ʻia. ʻO ka ʻoihana maoli ka loaʻa ʻana o ke kūlana win-win, inā hiki, makemake mākou e hāʻawi i ke kākoʻo hou aku no nā mea kūʻai aku. Welina mai nā mea kūʻai maikaʻi a pau e kamaʻilio i nā kikoʻī o nā mea kūʻai me mākou!!
